Multi-center and internal clinical registries help doctors and researchers improve the quality and safety of the care they provide to their patients. To this end, Methodist Digestive Institute (MDI) physicians initiate and participate in clinical databases and registries that involve regional, national, and even international institutions. Dr Kedia is leading the following research initiatives at Methodist Dallas Medical Center to advance the field of advanced endoscopy and improve the care of his patients
This is a prospective registry enrolling all patients at Methodist Dallas with a diagnosis of achalasia who undergo peroral endoscopic myotomy (POEM) for definitive minimally invasive treatment of this disease. The purpose of this registry is to further study the clinical efficacy, safety, and outcomes of patients undergoing the POEM procedure.
Multiple therapeutic procedures are performed with endoscopic ultrasound at Methodist Dallas including:
1) pancreatic fluid collection drainage
2) pancreaticobiliary duct drainage
3) gastric varices embolization
4) gallbladder drainage.
The purpose of this prospective registry is to further study these emerging techniques in terms of technical feasibility, clinical efficacy, safety, and long-term outcomes of patients undergoing therapeutic EUS procedures.
Endoscopic suturing is a novel technique that is being performed at Methodist Dallas for a variety of indications including:
1) securing lumenal metal stents;
2) closure of lumenal leaks/fistulas/perforations;
3) revision of gastrojejunal anastomoses in gastric bypass;
4) primary bariatric procedures.
The purpose of this prospective registry is to further study these emerging techniques in terms of technical feasibility, clinical efficacy, safety, and long-term outcomes of patients undergoing endoscopic suturing
Radiofrequency ablation for treatment of malignant biliary strictures is a novel technology with the potential to improve biliary patency in addition to the usage of bile duct stents. The purpose of this prospective registry is to enroll all patients with malignant biliary strictures who are undergoing repeated biliary stenting to assess the additional benefit of radiofrequency ablation on biliary patency.
For patients with acute or chronic cholecystitis who are not surgical candidates, endoscopic drainage of the gallbladder via transcystic duct stenting through endoscopic retrograde cholangio-pancreatography (ERCP) is being performed at Methodist Dallas. This is a minimally invasive alternative to percutaneous drainage of the gallbladder with possible benefits of less pain, fewer procedures, and reduced adverse events. The purpose of this prospective registry is to study the technical feasibility, clinical efficacy, safety, and longterm outcomes of non-surgical patients undergoing endoscopic gallbladder drainage for cholecystitis.
Transcutaneous liver biopsy has limitations in terms of body habitus, pain, and complications (including bleeding). Endoscopic ultrasound (EUS)-guided liver biopsy has been shown in early studies to be an effective alternative with a minimally invasive approach. The purpose of this prospective registry is to study the technical feasibility, diagnostic adequacy, and safety of patients undergoing endoscopic ultrasound-guided liver biopsy for the evaluation of hepatic disorders.